Winning the Fight Against COVID-19 Infection
Antibodies in our blood are the hallmark of protection against infection. Depending on antibody response, MRNA (Messenger Ribonucleic Acid) COVID-19 vaccines such as those created by Pfizer or Moderna are preferred. The more antibody producing vaccines are considered to provide higher protection. However recent evidence shows that in the absence of large antibody response, T cells can protect against SARS-CoV-2 (COVID-19) virus infection. T cells recognize the part of virus that does not undergo rapid mutation. Thus, a vaccine that can induce T cell response against the virus could be a longer lasting solution to frequently mutating SARS-COV-2 virus. Vaccines designed to produce a strong T cell response may be able to help protect against current and future variants of the virus that causes COVID-19. Early during the pandemic, the vaccines were developed to produce antibodies against a specific protein (SPIKE). However, as the SARS-CoV-2 virus mutates and alters spike proteins, the earlier vaccines became less effective.
Thus, having T cell vaccine, currently in the testing phase, could be a silver lining to getting COVID-19 vaccine for every mutant strain.
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